Articular cartilage surface structure and function

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Surface structure of articular cartilage. Historical review.

In the previous paper it has been shown that the surfaces of articular cartilage in living mammals and birds are not smooth but are covered by a series of secondary irregularities and of 20 to 30 [km. tertiary undulations, both superimposed on the broad primary anatomical contours (Gardner and McGillivray, 1971). The experiments from which this evidence has been derived have drawn attention to ...

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Articular cartilage has a unique structure that makes it very different from any other tissues in the body. It has such specific roles and functions such as weight bearing with low frictional coefficient that the main bulk of its structure is based on that alone, thus making it a vascular, and thereby greatly limiting its self regeneration capabilities. This article aims to review the structure...

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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...

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PRG4 exchange between the articular cartilage surface and synovial fluid.

The boundary lubrication function of articular cartilage is mediated in part by proteoglycan 4 (PRG4) molecules, found both in synovial fluid (SF) and bound to the articular cartilage surface. Currently the mechanism by which PRG4 binds to the articular surface is not well understood. The objectives of this study were to determine (1) the effect of bathing fluid contents on PRG4 concentration a...

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ژورنال

عنوان ژورنال: Pferdeheilkunde Equine Medicine

سال: 1993

ISSN: 0177-7726

DOI: 10.21836/pem19930202